Hypoglycemic effect of Equisetum myriochaetum aerial parts on streptozotocin diabetic rats.

نویسندگان

  • A Andrade Cetto
  • H Wiedenfeld
  • M C Revilla
  • I A Sergio
چکیده

The hypoglycemic effect of water as well as butanolic extracts prepared from aerial parts of Equisetum myriochaetum (Equisetaceae) was examined in streptozotocin induced diabetic rats. A single oral administration of the water extract (WE) at doses of 7 and 13 mg/kg and of the butanol extract (BE) at doses of 8 and 16 mg/kg significantly (P<0.001) lowered the plasma glucose levels in diabetic rats after three hours of the administration. As a reference drug glibenclamide was used and showed, at a dose of 3 mg/kg, similar hypoglycemic effect like the tested extracts. Three kaempferol glucosides and one caffeoyl glucoside were isolated from the drug and were shown to be the main constituents in both extracts.

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عنوان ژورنال:
  • Journal of ethnopharmacology

دوره 72 1-2  شماره 

صفحات  -

تاریخ انتشار 2000