Hypoglycemic effect of Equisetum myriochaetum aerial parts on streptozotocin diabetic rats.
نویسندگان
چکیده
The hypoglycemic effect of water as well as butanolic extracts prepared from aerial parts of Equisetum myriochaetum (Equisetaceae) was examined in streptozotocin induced diabetic rats. A single oral administration of the water extract (WE) at doses of 7 and 13 mg/kg and of the butanol extract (BE) at doses of 8 and 16 mg/kg significantly (P<0.001) lowered the plasma glucose levels in diabetic rats after three hours of the administration. As a reference drug glibenclamide was used and showed, at a dose of 3 mg/kg, similar hypoglycemic effect like the tested extracts. Three kaempferol glucosides and one caffeoyl glucoside were isolated from the drug and were shown to be the main constituents in both extracts.
منابع مشابه
Hypoglycemic effect of Equisetum myriochaetum aerial parts on type 2 diabetic patients.
The hypoglycemic effect of a water extract from aerial parts (0.33 g/kg) of Equisetum myriochaetum Schlecht and Cham (Equisetaceae) was analyzed in 11 recently diagnosed type 2 diabetic patients. A single dose of this extract was orally administered. Glucose and insulin were determined at 0, 30, 60, 90,120 and 180 min after administration. The same patients served as the control group and recei...
متن کاملبررسی اثر هایپوگلیسمیک عصاره اتانولی قسمتهای هوایی
Background and Aim: The use of medicinal plants has increased greatly mainly due to their easy availability, fewer side effects and lack of toxicity. The present study was carried out to investigate the antidiabetic effect of the extract of aerial parts of salvia nemorosa in normal and streptozotocin- induced diabetic male rats. Materials and Methods: After collection and taxonomic identificat...
متن کاملThe effect of Nepeta menthoides aerial parts hydroalcoholic extract on learning and memory in male streptozotocin-induced diabetic rat
Background and Objective: Diabetes mellitus is a common metabolic disorder that causes undesirable effects including learning and memory impairment. It has been reported that Nepeta menthoides improves memory and learning. Therefore, the aim of this study was to evaluate the effects of Nepeta menthoides on learning and memory impairment related to diabetes in rats. Materials and Methods: F...
متن کاملAntidiabetic and antihyperlipidemic activity of Euphorbia thymifolia L. extracts on streptozotocin-nicotinamide induced type 2 diabetic rats
Article history: Received on: 21/03/2017 Accepted on: 25/05/2017 Available online: 30/08/2017 The present investigation is aimed to elucidate the hypoglycaemic and hypolipidemic effect of the aqueous and methanol extract of Euphorbia thymifolia (ET) aerial parts in streptozotocin-nicotinamide (STZ-NA) induced diabetic rats. Diabetes was induced by administration of STZ (65 mg/kg, i.p.) followed...
متن کاملHypoglycemic Activity of Ethanolic Extract of Cinnamomum tamala Leaves in Normal and Streptozotocin Diabetic Rats
Indian traditional system of medicine has been used plants and herbs for treatment of diabetes since time of Vedic glory. In this regard many plants still untouched, having remarkable efficacy. The blood sugar lowering effect of 95% ethanolic extract of C. tamala ( Hamm.) Nees. & Eberm., leaves was investigated at single oral dose of 250mg/kg body weight in normal fasted, fed, glucose loaded...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of ethnopharmacology
دوره 72 1-2 شماره
صفحات -
تاریخ انتشار 2000